Themayhemandmadnesscontinueinseasonthreeofthisbitinganduproariousadultanimatedcomedyseries.Wrappinguptheir“Eat.Bang!Kill.Tour,”HarleyQuinn(KaleyCuoco)andPoisonIvy(LakeBell)returntoGothamasthenewpowercoupleofDCvillainy.Alongwiththeirragtagcrew–KingShark(RonFunches),Clayface(AlanTudyk),FrankthePlant(JBSmoove)-"Harlivy"strivestobecomethebestversionofthemselveswhilealsoworkingtowardsIvy’slongdesiredplanoftransformingGothamintoanEdenparadise.
闻香楼头牌昭离惨死，痴情于她的孟大侠将乌芒等与昭离生前有纠葛的几人骗来并困于怀秀村，欲用乌诏葬歌为昭离复仇，但随着在场人的不断离奇死亡，众人才意识到真凶早已易容成在场的九人之一并操纵着复仇游戏。最终在乌芒的带领下，真相的谜团逐渐被揭开。